Motley Crüe stormed back into Las Vegas on September 12, 2025, kicking off their brand-new residency with a night that was equal parts heavy nostalgia and unapologetic rock spectacle. For Vince Neil, the concert carried extra weight—it marked his first major return to the stage after suffering a stroke over Christmas last year, which left him having to relearn how to walk. His resilience was on display as the band tore through a career-spanning setlist that reminded everyone why the Crüe still define chaos and excess in rock and roll.
The night opened with pure adrenaline as “Live Wire” ripped through the venue, followed by the hard-hitting “Wild Side” and “Too Fast for Love.” From there, the band dug deep into their catalog, blasting through “Don’t Go Away Mad (Just Go Away)” and “Saints of Los Angeles.” Fans were treated to the grit and swagger of “Looks That Kill” before the set shifted into a furious medley of cover songs—Gary Glitter’s “Rock and Roll, Part 2,” Brownsville Station’s “Smokin’ in the Boys Room,” The Beatles’ “Helter Skelter,” and the Sex Pistols’ “Anarchy in the U.K.”
The energy didn’t let up as Nikki Sixx and Tommy Lee powered the band through staples like “Home Sweet Home,” “Dr. Feelgood,” “Same Ol’ Situation (S.O.S.),” and “Girls, Girls, Girls.” Each track drew deafening sing-alongs, with Sixx even demanding that the entire arena stand up—“even you in the expensive seats”—to keep the fire alive.
As the night roared to its climax, the band delivered their signature closer, “Kickstart My Heart,” sending the crowd home buzzing after nearly two hours of unrelenting rock.
Here’s the full setlist from Motley Crüe’s opening night at the Virgin Hotels Theater, Las Vegas, September 12, 2025:
- “Live Wire”
- “Wild Side”
- “Too Fast for Love”
- “Don’t Go Away Mad (Just Go Away)”
- “Saints of Los Angeles”
- “Looks That Kill”
- “Rock and Roll, Part 2” (Gary Glitter cover)
- “Smokin’ in the Boys Room” (Brownsville Station cover)
- “Helter Skelter” (The Beatles cover)
- “Anarchy in the U.K.” (Sex Pistols cover)
- “Home Sweet Home”
- “Dr. Feelgood”
- “Same Ol’ Situation (S.O.S.)”
- “Girls, Girls, Girls”
- “Kickstart My Heart”
Between the riffs, the fire, and the theatrics, this was more than just another Motley Crüe show. It was a defiant comeback, a reminder that even after setbacks and decades of chaos, the Crüe still know how to own Las Vegas like only they can.
